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Target Snapshot

CHEMBL612237 Target Snapshot

Human adenovirus 5 · ORGANISM · Human adenovirus 5

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404Compounds
98Assays
4Approved Drugs
245.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Human adenovirus 5 as ChEMBL target CHEMBL612237. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Human adenovirus 5
ORGANISM · Human adenovirus 5
As of 2026-09-14
ChEMBL target ID
CHEMBL612237
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Human adenovirus 5 still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

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Evidence Card
Review-ready rationale with source-aware context

Open the one-page evidence card when you want the rationale, activity base, and attribution together.

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameHuman adenovirus 5
Target TypeORGANISM
OrganismHuman adenovirus 5
ChEMBL ↗ NCBI Taxonomy ↗

Next Actions

SearchRun a focused querySearch the database using this target name as the starting context. ApprovalsCheck approved moleculesSee which approved drugs connect back to this target and its surrounding signal space. FeedScan papers & updatesStay in the project thread while checking recent papers and platform updates.
UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelHuman adenovirus 5
UniProt AccessionN/A

Human adenovirus 5

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as Human adenovirus 5.

Review nameHuman adenovirus 5
OrganismHuman adenovirus 5
Clinical Profile

Clinical Phase Distribution

4
Approved
1
Phase I
Assay Mix

Activity Type Distribution

IC50219.0
EC5026.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL4553793 7.3 IC50 50.0 Preclinical
CHEMBL536151 7.22 IC50 60.0 Preclinical
CHEMBL2313077 7.1 IC50 80.0 Preclinical
CHEMBL2088010 6.96 IC50 110.0 Preclinical
CHEMBL4448375 6.96 IC50 110.0 Preclinical
CHEMBL5631918 6.87 IC50 134.0 Preclinical
CHEMBL4460349 6.8 IC50 160.0 Preclinical
CHEMBL5631616 6.8 IC50 157.0 Preclinical
CHEMBL5632979 6.8 IC50 157.0 Preclinical
CHEMBL4474737 6.75 IC50 180.0 Preclinical
Distribution

pChEMBL Value Distribution

35
5.0
84
5.5
30
6.0
20
6.5
3
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

BRINCIDOFOVIR
CHEMBL203321
Approved 2021
Properties Compare Identifier
NICLOSAMIDE
CHEMBL1448
Approved 1982
Properties Compare Identifier
Assay Landscape

Assay Landscape

98
Total Assays
154
Tested Compounds
1
Assay Types
Functional — 98 assays, 154 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 98 154 5.7

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine