KG-1 · CELL-LINE · Homo sapiens
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KG-1
Review this target as KG-1.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats KG-1 as ChEMBL target CHEMBL612264. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | KG-1 |
| Target Type | CELL-LINE |
| Organism | Homo sapiens |
Reviewable protein naming and mapping context for this target snapshot.
Review this target as KG-1.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4790597 | 10.09 | IC50 | 0.081 | Preclinical |
| CHEMBL576982 | 9.8 | IC50 | 0.16 | Approved |
| CHEMBL4448252 | 9.4 | IC50 | 0.4 | Preclinical |
| CHEMBL5633382 | 9.3 | IC50 | 0.5 | Preclinical |
| CHEMBL4765060 | 9.26 | IC50 | 0.556 | Preclinical |
| CHEMBL4541330 | 9.22 | IC50 | 0.6 | Preclinical |
| CHEMBL4764390 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL65 | 8.96 | IC50 | 1.11 | Preclinical |
| CHEMBL888 | 8.74 | IC50 | 1.8 | Approved |
| CHEMBL3348846 | 8.72 | IC50 | 1.9 | Clinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 160 | 495 | 6.1 |
| organism-based format | 10 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 0 | — |