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Target Snapshot

CHEMBL612328 Target Snapshot

Plasmodium yoelii yoelii · ORGANISM · Plasmodium yoelii yoelii

Back to Search Search this target Browse approvals Evidence Card
56Compounds
16Assays
13Approved Drugs
66.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Plasmodium yoelii yoelii as ChEMBL target CHEMBL612328. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Plasmodium yoelii yoelii
ORGANISM · Plasmodium yoelii yoelii
As of 2026-09-13
ChEMBL target ID
CHEMBL612328
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Plasmodium yoelii yoelii still has a stable protein naming contract across sources.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NamePlasmodium yoelii yoelii
Target TypeORGANISM
OrganismPlasmodium yoelii yoelii
ChEMBL ↗ NCBI Taxonomy ↗

Next Actions

SearchRun a focused querySearch the database using this target name as the starting context. ApprovalsCheck approved moleculesSee which approved drugs connect back to this target and its surrounding signal space. FeedScan papers & updatesStay in the project thread while checking recent papers and platform updates.
UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelPlasmodium yoelii yoelii
UniProt AccessionN/A

Plasmodium yoelii yoelii

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as Plasmodium yoelii yoelii.

Review namePlasmodium yoelii yoelii
OrganismPlasmodium yoelii yoelii
Clinical Profile

Clinical Phase Distribution

13
Approved
1
Phase III
1
Phase II
Assay Mix

Activity Type Distribution

IC5066.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL593 9.07 IC50 0.846 Approved
CHEMBL45816 9.06 IC50 0.873 Approved
CHEMBL139702 9.03 IC50 0.927 Preclinical
CHEMBL91 8.69 IC50 2.03 Approved
CHEMBL926 8.43 IC50 3.7 Approved
CHEMBL163 7.47 IC50 34.2 Approved
CHEMBL114 7.45 IC50 35.2 Approved
CHEMBL959 7.45 IC50 35.6 Approved
CHEMBL1450 7.24 IC50 57.0 Approved
CHEMBL506 7.12 IC50 75.7 Approved
Distribution

pChEMBL Value Distribution

8
5.0
1
5.5
1
6.0
0
6.5
7
7.0
0
7.5
2
8.0
1
8.5
6
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

DELAVIRDINE
CHEMBL593
Approved 1997
Properties Compare Identifier
MIBEFRADIL
CHEMBL45816
Approved 1997
Properties Compare Identifier
RITONAVIR
CHEMBL163
Approved 1996
Properties Compare Identifier
SAQUINAVIR
CHEMBL114
Approved 1995
Properties Compare Identifier
RIMANTADINE
CHEMBL959
Approved 1993
Properties Compare Identifier
ATOVAQUONE
CHEMBL1450
Approved 1992
Properties Compare Identifier
DOBUTAMINE
CHEMBL926
Approved 1978
Properties Compare Identifier
MICONAZOLE
CHEMBL91
Approved 1974
Properties Compare Identifier
PRIMAQUINE
CHEMBL506
Approved 1952
Properties Compare Identifier
Assay Landscape

Assay Landscape

16
Total Assays
24
Tested Compounds
1
Assay Types
Functional — 16 assays, 24 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 16 24 6.5

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine