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Target Snapshot

CHEMBL612436 Target Snapshot

Enterovirus A71 · ORGANISM · Enterovirus A71

883Compounds
252Assays
6Approved Drugs
1,140.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Enterovirus A71 as ChEMBL target CHEMBL612436. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Enterovirus A71
ORGANISM · Enterovirus A71
As of 2026-09-14
ChEMBL target ID
CHEMBL612436
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

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Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Enterovirus A71 still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelEnterovirus A71
UniProt AccessionN/A

Enterovirus A71

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Enterovirus A71.

Review nameEnterovirus A71
OrganismEnterovirus A71
Clinical Profile

Clinical Phase Distribution

6
Approved
9
Phase II
Assay Mix

Activity Type Distribution

IC50254.0
EC50886.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL4468418 9.7 EC50 0.2 Preclinical
CHEMBL195749 9.3 EC50 0.5 Preclinical
CHEMBL372937 9.05 EC50 0.9 Preclinical
CHEMBL365461 9.0 IC50 1.0 Preclinical
CHEMBL4542009 9.0 EC50 1.0 Preclinical
CHEMBL4538215 8.85 EC50 1.4 Preclinical
CHEMBL4520449 8.7 EC50 2.0 Preclinical
CHEMBL5179843 8.7 EC50 2.0 Preclinical
CHEMBL194616 8.59 IC50 2.6 Preclinical
CHEMBL4454780 8.4 EC50 4.0 Preclinical
Distribution

pChEMBL Value Distribution

117
5.0
144
5.5
144
6.0
100
6.5
96
7.0
30
7.5
20
8.0
10
8.5
6
9.0
2
9.5
pChEMBL
Approved Drugs

Approved Drugs

REMDESIVIR
CHEMBL4065616
Approved 2020
Assay Landscape

Assay Landscape

252
Total Assays
583
Tested Compounds
1
Assay Types
Functional — 252 assays, 583 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 243 529 6.1
assay format 6 1 5.5
cell-based format 3 53 5.9

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine