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Target Snapshot

CHEMBL612462 Target Snapshot

Enterovirus C · ORGANISM · Enterovirus C

272Compounds
132Assays
2Approved Drugs
160.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Enterovirus C as ChEMBL target CHEMBL612462. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Enterovirus C
ORGANISM · Enterovirus C
As of 2026-09-13
ChEMBL target ID
CHEMBL612462
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Enterovirus C still has a stable protein naming contract across sources.

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Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelEnterovirus C
UniProt AccessionN/A

Enterovirus C

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Enterovirus C.

Review nameEnterovirus C
OrganismEnterovirus C
Clinical Profile

Clinical Phase Distribution

2
Approved
1
Phase II
Assay Mix

Activity Type Distribution

IC5023.0
EC50137.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL1235858 8.52 EC50 3.0 Preclinical
CHEMBL1269812 7.96 IC50 11.0 Preclinical
CHEMBL267099 7.52 IC50 30.0 Preclinical
CHEMBL108922 7.09 IC50 82.0 Preclinical
CHEMBL888 6.52 IC50 300.0 Approved
CHEMBL570510 6.06 EC50 870.0 Preclinical
CHEMBL570511 6.06 EC50 870.0 Preclinical
CHEMBL1269736 6.0 IC50 1010.0 Preclinical
CHEMBL570059 5.99 EC50 1030.0 Preclinical
CHEMBL584953 5.71 EC50 1950.0 Preclinical
Distribution

pChEMBL Value Distribution

1
5.0
5
5.5
3
6.0
3
6.5
9
7.0
30
7.5
6
8.0
2
8.5
0
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

GEMCITABINE
CHEMBL888
Approved 1996
Assay Landscape

Assay Landscape

132
Total Assays
20
Tested Compounds
2
Assay Types
Functional — 131 assays, 20 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 129 20 7.1
assay format 1 0
cell-based format 1 0
ADME — 1 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 1 0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine