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Target Snapshot

CHEMBL612464 Target Snapshot

rhinovirus A45 · ORGANISM · rhinovirus A45

19Compounds
6Assays
0Approved Drugs
21.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats rhinovirus A45 as ChEMBL target CHEMBL612464. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
rhinovirus A45
ORGANISM · rhinovirus A45
As of 2026-09-13
ChEMBL target ID
CHEMBL612464
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether rhinovirus A45 still has a stable protein naming contract across sources.

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Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein Labelrhinovirus A45
UniProt AccessionN/A

rhinovirus A45

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as rhinovirus A45.

Review namerhinovirus A45
Organismrhinovirus A45
Clinical Profile

Clinical Phase Distribution

2
Phase II
Assay Mix

Activity Type Distribution

EC5021.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL2407818 7.6 EC50 25.0 Preclinical
CHEMBL5432195 7.21 EC50 62.0 Preclinical
CHEMBL5618151 6.92 EC50 119.0 Preclinical
CHEMBL2397310 6.87 EC50 135.0 Preclinical
CHEMBL2397309 6.7 EC50 200.0 Preclinical
CHEMBL283403 6.6 EC50 250.0 Clinical
CHEMBL2397313 6.5 EC50 320.0 Preclinical
CHEMBL2397305 6.46 EC50 350.0 Preclinical
CHEMBL2397306 6.44 EC50 360.0 Preclinical
CHEMBL2397312 6.41 EC50 390.0 Preclinical
Distribution

pChEMBL Value Distribution

1
5.0
1
5.5
9
6.0
5
6.5
1
7.0
1
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

6
Total Assays
17
Tested Compounds
1
Assay Types
Functional — 6 assays, 17 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 6 17 6.5

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine