TF-1 · CELL-LINE · Homo sapiens
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TF-1
Review this target as TF-1.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats TF-1 as ChEMBL target CHEMBL612552. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | TF-1 |
| Target Type | CELL-LINE |
| Organism | Homo sapiens |
Reviewable protein naming and mapping context for this target snapshot.
Review this target as TF-1.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4790597 | 9.54 | IC50 | 0.288 | Preclinical |
| CHEMBL1835870 | 9.3 | IC50 | 0.5 | Preclinical |
| CHEMBL1835746 | 9.15 | IC50 | 0.7 | Preclinical |
| CHEMBL4764390 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL4444886 | 8.76 | IC50 | 1.75 | Preclinical |
| CHEMBL1835867 | 8.52 | IC50 | 3.0 | Preclinical |
| CHEMBL4765060 | 8.28 | IC50 | 5.306 | Preclinical |
| CHEMBL1835749 | 8.22 | IC50 | 6.0 | Preclinical |
| CHEMBL1835747 | 8.15 | IC50 | 7.0 | Preclinical |
| CHEMBL941 | 7.89 | IC50 | 13.0 | Approved |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 44 | 66 | 6.6 |
| organism-based format | 2 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 2 | 0 | — |