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Target Snapshot

CHEMBL612610 Target Snapshot

Influenza A virus (A/Puerto Rico/8/1934(H1N1)) · ORGANISM · Influenza A virus (A/Puerto Rico/8/1934(H1N1))

83Compounds
15Assays
7Approved Drugs
95.0Activities
Free Research Context

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Broader Open DB context

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Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

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Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Influenza A virus (A/Puerto Rico/8/1934(H1N1)) as ChEMBL target CHEMBL612610. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
ORGANISM · Influenza A virus (A/Puerto Rico/8/1934(H1N1))
As of 2026-09-13
ChEMBL target ID
CHEMBL612610
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Influenza A virus (A/Puerto Rico/8/1934(H1N1)) still has a stable protein naming contract across sources.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelInfluenza A virus (A/Puerto Rico/8/1934(H1N1))
UniProt AccessionN/A

Influenza A virus (A/Puerto Rico/8/1934(H1N1))

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Influenza A virus (A/Puerto Rico/8/1934(H1N1)).

Review nameInfluenza A virus (A/Puerto Rico/8/1934(H1N1))
OrganismInfluenza A virus (A/Puerto Rico/8/1934(H1N1))
Clinical Profile

Clinical Phase Distribution

7
Approved
1
Phase II
Assay Mix

Activity Type Distribution

IC5036.0
EC5059.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL466246 8.62 IC50 2.4 Clinical
CHEMBL222813 8.0 IC50 10.0 Approved
CHEMBL114999 7.22 EC50 60.0 Preclinical
CHEMBL1084494 7.1 EC50 80.0 Preclinical
CHEMBL1084225 7.01 EC50 98.0 Preclinical
CHEMBL1086593 6.75 EC50 180.0 Preclinical
CHEMBL1083936 6.72 EC50 190.0 Preclinical
CHEMBL1084488 6.62 EC50 240.0 Preclinical
CHEMBL1084491 6.58 EC50 260.0 Preclinical
CHEMBL1083323 6.57 EC50 270.0 Preclinical
Distribution

pChEMBL Value Distribution

8
5.0
7
5.5
8
6.0
6
6.5
3
7.0
0
7.5
1
8.0
1
8.5
0
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

ZANAMIVIR
CHEMBL222813
Approved 1999
Assay Landscape

Assay Landscape

15
Total Assays
65
Tested Compounds
1
Assay Types
Functional — 15 assays, 65 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 15 65 5.3

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine