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Target Snapshot

CHEMBL612640 Target Snapshot

Mycobacterium intracellulare · ORGANISM · Mycobacterium intracellulare

Back to Search Search this target Browse approvals Evidence Card
992Compounds
123Assays
1Approved Drugs
386.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Mycobacterium intracellulare as ChEMBL target CHEMBL612640. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Mycobacterium intracellulare
ORGANISM · Mycobacterium intracellulare
As of 2026-09-13
ChEMBL target ID
CHEMBL612640
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Mycobacterium intracellulare still has a stable protein naming contract across sources.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameMycobacterium intracellulare
Target TypeORGANISM
OrganismMycobacterium intracellulare
ChEMBL ↗ NCBI Taxonomy ↗

Next Actions

SearchRun a focused querySearch the database using this target name as the starting context. ApprovalsCheck approved moleculesSee which approved drugs connect back to this target and its surrounding signal space. FeedScan papers & updatesStay in the project thread while checking recent papers and platform updates.
UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelMycobacterium intracellulare
UniProt AccessionN/A

Mycobacterium intracellulare

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as Mycobacterium intracellulare.

Review nameMycobacterium intracellulare
OrganismMycobacterium intracellulare
Clinical Profile

Clinical Phase Distribution

1
Approved
Assay Mix

Activity Type Distribution

IC50386.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL595533 7.52 IC50 30.0 Preclinical
CHEMBL509849 6.89 IC50 130.0 Preclinical
CHEMBL403233 6.75 IC50 180.0 Preclinical
CHEMBL612054 6.75 IC50 177.0 Preclinical
CHEMBL488771 6.44 IC50 360.0 Preclinical
CHEMBL8 6.38 IC50 420.0 Approved
CHEMBL608123 6.29 IC50 508.0 Preclinical
CHEMBL608121 6.27 IC50 540.0 Preclinical
CHEMBL608119 6.16 IC50 695.0 Preclinical
CHEMBL595418 6.06 IC50 868.0 Preclinical
Distribution

pChEMBL Value Distribution

4
5.0
14
5.5
11
6.0
3
6.5
0
7.0
1
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

CIPROFLOXACIN
CHEMBL8
Approved 1987
Properties Compare Identifier
Assay Landscape

Assay Landscape

123
Total Assays
37
Tested Compounds
2
Assay Types
Functional — 122 assays, 37 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 117 37 5.6
cell-based format 5 0 —
ADME — 1 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 1 0 —

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine