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Target Snapshot

CHEMBL612670 Target Snapshot

Felis catus · ORGANISM · Felis catus

Back to Search Search this target Browse approvals Evidence Card
1,549Compounds
968Assays
5Approved Drugs
174.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Felis catus as ChEMBL target CHEMBL612670. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Felis catus
ORGANISM · Felis catus
As of 2026-09-14
ChEMBL target ID
CHEMBL612670
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Felis catus still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameFelis catus
Target TypeORGANISM
OrganismFelis catus
ChEMBL ↗ NCBI Taxonomy ↗

Next Actions

SearchRun a focused querySearch the database using this target name as the starting context. ApprovalsCheck approved moleculesSee which approved drugs connect back to this target and its surrounding signal space. FeedScan papers & updatesStay in the project thread while checking recent papers and platform updates.
UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelFelis catus
UniProt AccessionN/A

Felis catus

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as Felis catus.

Review nameFelis catus
OrganismFelis catus
Clinical Profile

Clinical Phase Distribution

5
Approved
1
Phase III
3
Phase II
Assay Mix

Activity Type Distribution

IC5070.0
EC5082.0
KD22.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL165590 10.7 IC50 0.02 Preclinical
CHEMBL169992 10.4 IC50 0.04 Preclinical
CHEMBL167245 10.0 IC50 0.1 Preclinical
CHEMBL168310 10.0 IC50 0.1 Preclinical
CHEMBL1397882 9.52 IC50 0.3 Preclinical
CHEMBL167244 9.3 IC50 0.5 Preclinical
CHEMBL102221 9.15 EC50 0.71 Preclinical
CHEMBL1050 9.15 EC50 0.71 Preclinical
CHEMBL170217 9.15 IC50 0.7 Preclinical
CHEMBL152717 9.0 IC50 1.0 Preclinical
Distribution

pChEMBL Value Distribution

21
5.0
10
5.5
10
6.0
9
6.5
10
7.0
3
7.5
10
8.0
3
8.5
9
9.0
2
9.5
pChEMBL
Approved Drugs

Approved Drugs

DINOPROST
CHEMBL815
Approved 1982
Properties Compare Identifier
ETHACRYNIC ACID
CHEMBL456
Approved 1967
Properties Compare Identifier
PRACTOLOL
CHEMBL6995
Properties Compare Identifier
Assay Landscape

Assay Landscape

968
Total Assays
86
Tested Compounds
4
Assay Types
Functional — 950 assays, 86 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 950 86 6.6
ADME — 10 assays, 2 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 10 2 5.2
Toxicity — 7 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 7 0 —
Unassigned — 1 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 1 0 —

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine