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Target Snapshot

CHEMBL612688 Target Snapshot

Anolis carolinensis · ORGANISM · Anolis carolinensis

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22Compounds
7Assays
0Approved Drugs
12.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Anolis carolinensis as ChEMBL target CHEMBL612688. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Anolis carolinensis
ORGANISM · Anolis carolinensis
As of 2026-09-14
ChEMBL target ID
CHEMBL612688
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Anolis carolinensis still has a stable protein naming contract across sources.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameAnolis carolinensis
Target TypeORGANISM
OrganismAnolis carolinensis
ChEMBL ↗ NCBI Taxonomy ↗

Next Actions

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelAnolis carolinensis
UniProt AccessionN/A

Anolis carolinensis

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as Anolis carolinensis.

Review nameAnolis carolinensis
OrganismAnolis carolinensis
Clinical Profile

Clinical Phase Distribution

1
Phase II
Assay Mix

Activity Type Distribution

EC5012.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL427615 11.0 EC50 0.01 Preclinical
CHEMBL430239 10.96 EC50 0.011 Preclinical
CHEMBL2370759 10.3 EC50 0.05 Preclinical
CHEMBL387404 9.96 EC50 0.11 Preclinical
CHEMBL2370760 9.77 EC50 0.17 Preclinical
CHEMBL2370756 9.7 EC50 0.2 Preclinical
CHEMBL410200 9.7 EC50 0.2 Preclinical
CHEMBL214332 9.0 EC50 1.0 Clinical
CHEMBL410174 9.0 EC50 1.0 Preclinical
CHEMBL415672 9.0 EC50 1.0 Preclinical
Distribution

pChEMBL Value Distribution

0
5.0
0
5.5
0
6.0
0
6.5
0
7.0
0
7.5
1
8.0
1
8.5
3
9.0
4
9.5
pChEMBL
Assay Landscape

Assay Landscape

7
Total Assays
12
Tested Compounds
1
Assay Types
Functional — 7 assays, 12 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 7 12 9.6

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine