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Target Snapshot

CHEMBL612707 Target Snapshot

GLC4 cell line · CELL-LINE · Homo sapiens

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22Compounds
2Assays
3Approved Drugs
35.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats GLC4 cell line as ChEMBL target CHEMBL612707. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
GLC4 cell line
CELL-LINE · Homo sapiens
As of 2026-09-14
ChEMBL target ID
CHEMBL612707
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether GLC4 cell line still has a stable protein naming contract across sources.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameGLC4 cell line
Target TypeCELL-LINE
OrganismHomo sapiens
ChEMBL ↗

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelGLC4 cell line
UniProt AccessionN/A

GLC4 cell line

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as GLC4 cell line.

Review nameGLC4 cell line
OrganismHomo sapiens
Clinical Profile

Clinical Phase Distribution

3
Approved
Assay Mix

Activity Type Distribution

IC5035.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL63970 8.1 IC50 8.0 Preclinical
CHEMBL28941 7.52 IC50 30.0 Preclinical
CHEMBL292945 7.22 IC50 60.0 Preclinical
CHEMBL61 7.22 IC50 60.0 Approved
CHEMBL452231 6.32 IC50 480.0 Approved
CHEMBL44657 6.09 IC50 820.0 Approved
CHEMBL67077 6.08 IC50 830.0 Preclinical
CHEMBL302952 5.77 IC50 1700.0 Preclinical
CHEMBL63962 5.19 IC50 6500.0 Preclinical
CHEMBL304828 5.06 IC50 8800.0 Preclinical
Distribution

pChEMBL Value Distribution

7
5.0
4
5.5
3
6.0
3
6.5
2
7.0
1
7.5
1
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

TENIPOSIDE
CHEMBL452231
Approved 1992
Properties Compare Identifier
PODOFILOX
CHEMBL61
Approved 1990
Properties Compare Identifier
ETOPOSIDE
CHEMBL44657
Approved 1983
Properties Compare Identifier
Assay Landscape

Assay Landscape

2
Total Assays
20
Tested Compounds
1
Assay Types
Functional — 2 assays, 20 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 2 20 5.5

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine