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Target Snapshot

CHEMBL612725 Target Snapshot

Eastern equine encephalitis virus · ORGANISM · Eastern equine encephalitis virus

Back to Search Search this target Browse approvals Evidence Card
21Compounds
6Assays
1Approved Drugs
21.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Eastern equine encephalitis virus as ChEMBL target CHEMBL612725. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Eastern equine encephalitis virus
ORGANISM · Eastern equine encephalitis virus
As of 2026-09-14
ChEMBL target ID
CHEMBL612725
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Eastern equine encephalitis virus still has a stable protein naming contract across sources.

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Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameEastern equine encephalitis virus
Target TypeORGANISM
OrganismEastern equine encephalitis virus
ChEMBL ↗ NCBI Taxonomy ↗

Next Actions

SearchRun a focused querySearch the database using this target name as the starting context. ApprovalsCheck approved moleculesSee which approved drugs connect back to this target and its surrounding signal space. FeedScan papers & updatesStay in the project thread while checking recent papers and platform updates.
UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelEastern equine encephalitis virus
UniProt AccessionN/A

Eastern equine encephalitis virus

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as Eastern equine encephalitis virus.

Review nameEastern equine encephalitis virus
OrganismEastern equine encephalitis virus
Clinical Profile

Clinical Phase Distribution

1
Approved
Assay Mix

Activity Type Distribution

EC5021.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL486477 8.7 EC50 2.0 Preclinical
CHEMBL5084707 7.57 EC50 27.0 Preclinical
CHEMBL5086104 7.48 EC50 33.0 Preclinical
CHEMBL5080159 7.23 EC50 59.0 Preclinical
CHEMBL5081454 6.96 EC50 110.0 Preclinical
CHEMBL5073057 6.8 EC50 160.0 Preclinical
CHEMBL5086133 6.58 EC50 260.0 Preclinical
CHEMBL5080706 6.52 EC50 300.0 Preclinical
CHEMBL5084039 6.3 EC50 500.0 Preclinical
CHEMBL5094162 5.72 EC50 1900.0 Preclinical
Distribution

pChEMBL Value Distribution

5
5.0
4
5.5
1
6.0
4
6.5
2
7.0
1
7.5
0
8.0
1
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

6
Total Assays
19
Tested Compounds
1
Assay Types
Functional — 6 assays, 19 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 6 19 6.2

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine