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Target Snapshot

CHEMBL612915 Target Snapshot

Leishmania tarentolae · ORGANISM · Leishmania tarentolae

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50Compounds
9Assays
1Approved Drugs
48.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Leishmania tarentolae as ChEMBL target CHEMBL612915. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Leishmania tarentolae
ORGANISM · Leishmania tarentolae
As of 2026-09-13
ChEMBL target ID
CHEMBL612915
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Leishmania tarentolae still has a stable protein naming contract across sources.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameLeishmania tarentolae
Target TypeORGANISM
OrganismLeishmania tarentolae
ChEMBL ↗ NCBI Taxonomy ↗

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelLeishmania tarentolae
UniProt AccessionN/A

Leishmania tarentolae

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as Leishmania tarentolae.

Review nameLeishmania tarentolae
OrganismLeishmania tarentolae
Clinical Profile

Clinical Phase Distribution

1
Approved
Assay Mix

Activity Type Distribution

IC5048.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL55 7.52 IC50 30.0 Approved
CHEMBL2435426 6.66 IC50 220.0 Preclinical
CHEMBL2435435 6.19 IC50 650.0 Preclinical
CHEMBL2435427 6.11 IC50 770.0 Preclinical
CHEMBL2435420 6.07 IC50 860.0 Preclinical
CHEMBL2435425 5.98 IC50 1040.0 Preclinical
CHEMBL2435419 5.93 IC50 1170.0 Preclinical
CHEMBL2435418 5.82 IC50 1530.0 Preclinical
CHEMBL2435423 5.75 IC50 1780.0 Preclinical
CHEMBL2435424 5.62 IC50 2400.0 Preclinical
Distribution

pChEMBL Value Distribution

11
5.0
5
5.5
3
6.0
1
6.5
0
7.0
1
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

PENTAMIDINE
CHEMBL55
Approved 1984
Properties Compare Identifier
Assay Landscape

Assay Landscape

9
Total Assays
47
Tested Compounds
1
Assay Types
Functional — 9 assays, 47 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 9 47 5.2

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine