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Target Snapshot

CHEMBL613064 Target Snapshot

Pneumocystis carinii · ORGANISM · Pneumocystis carinii

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424Compounds
127Assays
2Approved Drugs
358.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Pneumocystis carinii as ChEMBL target CHEMBL613064. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Pneumocystis carinii
ORGANISM · Pneumocystis carinii
As of 2026-09-14
ChEMBL target ID
CHEMBL613064
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Pneumocystis carinii still has a stable protein naming contract across sources.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NamePneumocystis carinii
Target TypeORGANISM
OrganismPneumocystis carinii
ChEMBL ↗ NCBI Taxonomy ↗

Next Actions

SearchRun a focused querySearch the database using this target name as the starting context. ApprovalsCheck approved moleculesSee which approved drugs connect back to this target and its surrounding signal space. FeedScan papers & updatesStay in the project thread while checking recent papers and platform updates.
UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelPneumocystis carinii
UniProt AccessionN/A

Pneumocystis carinii

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as Pneumocystis carinii.

Review namePneumocystis carinii
OrganismPneumocystis carinii
Clinical Profile

Clinical Phase Distribution

2
Approved
Assay Mix

Activity Type Distribution

IC50358.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL185063 9.52 IC50 0.3 Preclinical
CHEMBL185175 8.7 IC50 2.0 Preclinical
CHEMBL4278504 8.0 IC50 10.0 Preclinical
CHEMBL4281968 7.96 IC50 11.0 Preclinical
CHEMBL4293637 7.92 IC50 12.0 Preclinical
CHEMBL4279538 7.85 IC50 14.0 Preclinical
CHEMBL4294069 7.44 IC50 36.0 Preclinical
CHEMBL4290067 7.39 IC50 41.0 Preclinical
CHEMBL4289844 7.21 IC50 62.0 Preclinical
CHEMBL4290244 7.12 IC50 76.0 Preclinical
Distribution

pChEMBL Value Distribution

21
5.0
32
5.5
8
6.0
5
6.5
7
7.0
3
7.5
1
8.0
5
8.5
0
9.0
1
9.5
pChEMBL
Approved Drugs

Approved Drugs

PENTAMIDINE
CHEMBL55
Approved 1984
Properties Compare Identifier
Assay Landscape

Assay Landscape

127
Total Assays
99
Tested Compounds
2
Assay Types
Functional — 101 assays, 99 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 101 99 5.7
ADME — 26 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 26 0 —

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine