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Target Snapshot

CHEMBL613086 Target Snapshot

Mycobacterium tuberculosis variant bovis · ORGANISM · Mycobacterium tuberculosis variant bovis

997Compounds
264Assays
4Approved Drugs
169.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

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Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Mycobacterium tuberculosis variant bovis as ChEMBL target CHEMBL613086. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Mycobacterium tuberculosis variant bovis
ORGANISM · Mycobacterium tuberculosis variant bovis
As of 2026-09-14
ChEMBL target ID
CHEMBL613086
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Mycobacterium tuberculosis variant bovis still has a stable protein naming contract across sources.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelMycobacterium tuberculosis variant bovis
UniProt AccessionN/A

Mycobacterium tuberculosis variant bovis

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Mycobacterium tuberculosis variant bovis.

Review nameMycobacterium tuberculosis variant bovis
OrganismMycobacterium tuberculosis variant bovis
Clinical Profile

Clinical Phase Distribution

4
Approved
Assay Mix

Activity Type Distribution

IC50169.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL374478 8.0 IC50 10.0 Approved
CHEMBL3637787 7.0 IC50 100.0 Preclinical
CHEMBL216579 6.81 IC50 155.0 Preclinical
CHEMBL3984383 6.64 IC50 230.0 Preclinical
CHEMBL3982300 6.61 IC50 247.0 Preclinical
CHEMBL3975897 6.48 IC50 328.0 Preclinical
CHEMBL3891541 6.42 IC50 383.0 Preclinical
CHEMBL3929580 6.36 IC50 436.0 Preclinical
CHEMBL3971460 6.34 IC50 455.0 Preclinical
CHEMBL3985778 6.32 IC50 475.0 Preclinical
Distribution

pChEMBL Value Distribution

37
5.0
22
5.5
15
6.0
3
6.5
1
7.0
0
7.5
1
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

RIFAMPIN
CHEMBL374478
Approved 1971
Assay Landscape

Assay Landscape

264
Total Assays
90
Tested Compounds
2
Assay Types
Functional — 260 assays, 90 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 175 67 5.3
assay format 58 23 6.1
cell-based format 27 0
ADME — 4 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 4 0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine