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Target Snapshot

CHEMBL613140 Target Snapshot

Brugia malayi · ORGANISM · Brugia malayi

Back to Search Search this target Browse approvals Evidence Card
637Compounds
175Assays
0Approved Drugs
134.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Brugia malayi as ChEMBL target CHEMBL613140. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Brugia malayi
ORGANISM · Brugia malayi
As of 2026-09-14
ChEMBL target ID
CHEMBL613140
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Brugia malayi still has a stable protein naming contract across sources.

Jump to Protein Context
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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameBrugia malayi
Target TypeORGANISM
OrganismBrugia malayi
ChEMBL ↗ NCBI Taxonomy ↗

Next Actions

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelBrugia malayi
UniProt AccessionN/A

Brugia malayi

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as Brugia malayi.

Review nameBrugia malayi
OrganismBrugia malayi
Clinical Profile

Clinical Phase Distribution

1
Phase II
Assay Mix

Activity Type Distribution

IC50134.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL3416681 8.25 IC50 5.6 Preclinical
CHEMBL3416682 7.89 IC50 13.0 Preclinical
CHEMBL3416684 6.75 IC50 180.0 Preclinical
CHEMBL2093168 6.58 IC50 260.0 Preclinical
CHEMBL3416676 6.58 IC50 260.0 Preclinical
CHEMBL3416677 6.55 IC50 280.0 Preclinical
CHEMBL3416675 6.42 IC50 380.0 Preclinical
CHEMBL3416680 6.37 IC50 430.0 Preclinical
CHEMBL2093181 6.28 IC50 530.0 Preclinical
CHEMBL2093174 6.07 IC50 853.0 Preclinical
Distribution

pChEMBL Value Distribution

48
5.0
24
5.5
9
6.0
4
6.5
1
7.0
2
7.5
1
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

195
Total Assays
76
Tested Compounds
1
Assay Types
Functional — 195 assays, 76 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 193 76 5.7
assay format 1 0 —
tissue-based format 1 0 —

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine