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Target Snapshot

CHEMBL613360 Target Snapshot

dengue virus type 1 · ORGANISM · dengue virus type 1

Back to Search Search this target Browse approvals Evidence Card
263Compounds
81Assays
5Approved Drugs
265.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats dengue virus type 1 as ChEMBL target CHEMBL613360. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
dengue virus type 1
ORGANISM · dengue virus type 1
As of 2026-09-13
ChEMBL target ID
CHEMBL613360
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether dengue virus type 1 still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

Jump to Disease Context
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Evidence Card
Review-ready rationale with source-aware context

Open the one-page evidence card when you want the rationale, activity base, and attribution together.

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred Namedengue virus type 1
Target TypeORGANISM
Organismdengue virus type 1
ChEMBL ↗ NCBI Taxonomy ↗

Next Actions

SearchRun a focused querySearch the database using this target name as the starting context. ApprovalsCheck approved moleculesSee which approved drugs connect back to this target and its surrounding signal space. FeedScan papers & updatesStay in the project thread while checking recent papers and platform updates.
UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein Labeldengue virus type 1
UniProt AccessionN/A

dengue virus type 1

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as dengue virus type 1.

Review namedengue virus type 1
Organismdengue virus type 1
Clinical Profile

Clinical Phase Distribution

5
Approved
1
Phase III
3
Phase II
1
Phase I
Assay Mix

Activity Type Distribution

IC5039.0
EC50226.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL3905772 10.0 EC50 0.1 Preclinical
CHEMBL5314530 9.7 EC50 0.2 Clinical
CHEMBL5562312 9.52 EC50 0.3 Preclinical
CHEMBL3923294 9.4 EC50 0.4 Preclinical
CHEMBL5555759 9.4 EC50 0.4 Preclinical
CHEMBL3895322 9.05 EC50 0.9 Preclinical
CHEMBL5566989 9.0 EC50 1.0 Preclinical
CHEMBL3889668 8.7 EC50 2.0 Preclinical
CHEMBL3905304 8.7 EC50 2.0 Preclinical
CHEMBL5559307 8.7 EC50 2.0 Preclinical
Distribution

pChEMBL Value Distribution

42
5.0
58
5.5
35
6.0
11
6.5
10
7.0
2
7.5
6
8.0
5
8.5
5
9.0
2
9.5
pChEMBL
Approved Drugs

Approved Drugs

SUNITINIB
CHEMBL535
Approved 2006
Properties Compare Identifier
Assay Landscape

Assay Landscape

83
Total Assays
192
Tested Compounds
1
Assay Types
Functional — 83 assays, 192 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 81 161 6.0
cell-based format 2 31 5.8

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine