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Target Snapshot

CHEMBL613448 Target Snapshot

Gastric gland · TISSUE · Oryctolagus cuniculus

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144Compounds
4Assays
0Approved Drugs
134.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Gastric gland as ChEMBL target CHEMBL613448. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Gastric gland
TISSUE · Oryctolagus cuniculus
As of 2026-09-13
ChEMBL target ID
CHEMBL613448
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Gastric gland still has a stable protein naming contract across sources.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameGastric gland
Target TypeTISSUE
OrganismOryctolagus cuniculus
ChEMBL ↗

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelGastric gland
UniProt AccessionN/A

Gastric gland

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as Gastric gland.

Review nameGastric gland
OrganismOryctolagus cuniculus
Assay Mix

Activity Type Distribution

IC50134.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL394240 7.3 IC50 50.12 Preclinical
CHEMBL296482 7.2 IC50 63.1 Preclinical
CHEMBL391255 7.1 IC50 79.43 Preclinical
CHEMBL392580 7.0 IC50 100.0 Preclinical
CHEMBL391054 6.8 IC50 158.49 Preclinical
CHEMBL393803 6.7 IC50 199.53 Preclinical
CHEMBL240781 6.7 IC50 199.53 Preclinical
CHEMBL241005 6.7 IC50 199.53 Preclinical
CHEMBL391059 6.7 IC50 199.53 Preclinical
CHEMBL1095848 6.7 IC50 199.53 Preclinical
Distribution

pChEMBL Value Distribution

22
5.0
36
5.5
40
6.0
14
6.5
4
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

4
Total Assays
134
Tested Compounds
1
Assay Types
Functional — 4 assays, 134 compounds
BAO Format Assays Compounds Avg pChEMBL
tissue-based format 4 134 5.7

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine