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Target Snapshot

CHEMBL613469 Target Snapshot

Musca domestica · ORGANISM · Musca domestica

379Compounds
122Assays
0Approved Drugs
24.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Musca domestica as ChEMBL target CHEMBL613469. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Musca domestica
ORGANISM · Musca domestica
As of 2026-09-14
ChEMBL target ID
CHEMBL613469
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Musca domestica still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelMusca domestica
UniProt AccessionN/A

Musca domestica

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Musca domestica.

Review nameMusca domestica
OrganismMusca domestica
Assay Mix

Activity Type Distribution

EC5024.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL265941 6.37 EC50 426.58 Preclinical
CHEMBL406819 5.93 EC50 1174.9 Preclinical
CHEMBL2287445 5.52 EC50 3019.95 Preclinical
CHEMBL2287446 4.73 EC50 18620.87 Preclinical
CHEMBL2287448 4.46 EC50 34673.69 Preclinical
CHEMBL2287452 4.45 EC50 35481.34 Preclinical
Distribution

pChEMBL Value Distribution

0
5.0
2
5.5
1
6.0
0
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

122
Total Assays
18
Tested Compounds
2
Assay Types
Functional — 110 assays, 18 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 110 18 5.2
ADME — 12 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 12 0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine