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Target Snapshot

CHEMBL613502 Target Snapshot

UMR106-06 · CELL-LINE · Rattus norvegicus

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17Compounds
3Assays
0Approved Drugs
15.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats UMR106-06 as ChEMBL target CHEMBL613502. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
UMR106-06
CELL-LINE · Rattus norvegicus
As of 2026-09-14
ChEMBL target ID
CHEMBL613502
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether UMR106-06 still has a stable protein naming contract across sources.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameUMR106-06
Target TypeCELL-LINE
OrganismRattus norvegicus
ChEMBL ↗

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelUMR106-06
UniProt AccessionN/A

UMR106-06

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as UMR106-06.

Review nameUMR106-06
OrganismRattus norvegicus
Assay Mix

Activity Type Distribution

EC5015.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL276472 9.19 EC50 0.65 Preclinical
CHEMBL2370337 9.0 EC50 1.0 Preclinical
CHEMBL438942 8.92 EC50 1.2 Preclinical
CHEMBL439458 8.8 EC50 1.6 Preclinical
CHEMBL440239 8.59 EC50 2.6 Preclinical
CHEMBL2370336 8.48 EC50 3.3 Preclinical
CHEMBL414363 8.36 EC50 4.4 Preclinical
CHEMBL412178 8.31 EC50 4.9 Preclinical
CHEMBL424859 8.3 EC50 5.0 Preclinical
CHEMBL428635 7.89 EC50 13.0 Preclinical
Distribution

pChEMBL Value Distribution

0
5.0
0
5.5
1
6.0
0
6.5
0
7.0
4
7.5
5
8.0
3
8.5
2
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

3
Total Assays
14
Tested Compounds
2
Assay Types
Functional — 2 assays, 14 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 2 14 8.2
ADME — 1 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 1 0 —

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine