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Target Snapshot

CHEMBL613529 Target Snapshot

SNU-16 · CELL-LINE · Homo sapiens

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297Compounds
192Assays
19Approved Drugs
297.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats SNU-16 as ChEMBL target CHEMBL613529. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
SNU-16
CELL-LINE · Homo sapiens
As of 2026-09-13
ChEMBL target ID
CHEMBL613529
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether SNU-16 still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

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Evidence Card
Review-ready rationale with source-aware context

Open the one-page evidence card when you want the rationale, activity base, and attribution together.

Open Review-ready Card
Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameSNU-16
Target TypeCELL-LINE
OrganismHomo sapiens
ChEMBL ↗

Next Actions

SearchRun a focused querySearch the database using this target name as the starting context. ApprovalsCheck approved moleculesSee which approved drugs connect back to this target and its surrounding signal space. FeedScan papers & updatesStay in the project thread while checking recent papers and platform updates.
UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelSNU-16
UniProt AccessionN/A

SNU-16

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as SNU-16.

Review nameSNU-16
OrganismHomo sapiens
Clinical Profile

Clinical Phase Distribution

19
Approved
4
Phase III
6
Phase II
2
Phase I
Assay Mix

Activity Type Distribution

IC50295.0
EC502.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL5589978 9.68 IC50 0.207 Preclinical
CHEMBL4102642 9.52 IC50 0.3 Preclinical
CHEMBL4099992 9.3 IC50 0.5 Preclinical
CHEMBL3828009 9.29 IC50 0.511 Preclinical
CHEMBL4869917 9.17 IC50 0.67 Preclinical
CHEMBL3545376 9.15 IC50 0.7 Approved
CHEMBL5177696 9.15 IC50 0.7 Preclinical
CHEMBL4064081 9.05 IC50 0.9 Preclinical
CHEMBL4062003 8.92 IC50 1.2 Preclinical
CHEMBL3348846 8.92 IC50 1.2 Clinical
Distribution

pChEMBL Value Distribution

9
5.0
8
5.5
23
6.0
21
6.5
30
7.0
25
7.5
48
8.0
23
8.5
7
9.0
2
9.5
pChEMBL
Approved Drugs

Approved Drugs

FUTIBATINIB
CHEMBL3701238
Approved 2022
Properties Compare Identifier
INFIGRATINIB
CHEMBL1852688
Approved 2021
Properties Compare Identifier
PEMIGATINIB
CHEMBL4297522
Approved 2020
Properties Compare Identifier
TEPOTINIB
CHEMBL3402762
Approved 2020
Properties Compare Identifier
ERDAFITINIB
CHEMBL3545376
Approved 2019
Properties Compare Identifier
PONATINIB
CHEMBL1171837
Approved 2012
Properties Compare Identifier
VORINOSTAT
CHEMBL98
Approved 2006
Properties Compare Identifier
VINORELBINE
CHEMBL553025
Approved 1994
Properties Compare Identifier
PACLITAXEL
CHEMBL428647
Approved 1992
Properties Compare Identifier
Assay Landscape

Assay Landscape

194
Total Assays
236
Tested Compounds
1
Assay Types
Functional — 194 assays, 236 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 162 236 7.2
organism-based format 32 0 —

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine