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Target Snapshot

CHEMBL613530 Target Snapshot

SW 962 · CELL-LINE · Homo sapiens

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150Compounds
12Assays
31Approved Drugs
141.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats SW 962 as ChEMBL target CHEMBL613530. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
SW 962
CELL-LINE · Homo sapiens
As of 2026-09-14
ChEMBL target ID
CHEMBL613530
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether SW 962 still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameSW 962
Target TypeCELL-LINE
OrganismHomo sapiens
ChEMBL ↗

Next Actions

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelSW 962
UniProt AccessionN/A

SW 962

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as SW 962.

Review nameSW 962
OrganismHomo sapiens
Clinical Profile

Clinical Phase Distribution

31
Approved
13
Phase III
11
Phase II
4
Phase I
Assay Mix

Activity Type Distribution

IC50141.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL94657 8.98 IC50 1.036 Clinical
CHEMBL3545252 8.53 IC50 2.929 Approved
CHEMBL325041 8.28 IC50 5.208 Clinical
CHEMBL428647 8.18 IC50 6.623 Approved
CHEMBL96926 8.16 IC50 6.848 Preclinical
CHEMBL1201182 7.81 IC50 15.59 Approved
CHEMBL159 7.71 IC50 19.39 Approved
CHEMBL65 7.69 IC50 20.51 Preclinical
CHEMBL449158 7.63 IC50 23.36 Clinical
CHEMBL1879463 7.57 IC50 26.76 Clinical
Distribution

pChEMBL Value Distribution

19
5.0
11
5.5
7
6.0
5
6.5
8
7.0
7
7.5
3
8.0
2
8.5
0
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

PALBOCICLIB
CHEMBL189963
Approved 2015
Properties Compare Identifier
TEMSIROLIMUS
CHEMBL1201182
Approved 2007
Properties Compare Identifier
DASATINIB
CHEMBL5416410
Approved 2006
Properties Compare Identifier
SIROLIMUS
CHEMBL413
Approved 1999
Properties Compare Identifier
GEMCITABINE
CHEMBL888
Approved 1996
Properties Compare Identifier
DOCETAXEL
CHEMBL3545252
Approved 1995
Properties Compare Identifier
VINORELBINE
CHEMBL553025
Approved 1994
Properties Compare Identifier
PACLITAXEL
CHEMBL428647
Approved 1992
Properties Compare Identifier
MITOMYCIN
CHEMBL105
Approved 1981
Properties Compare Identifier
DOXORUBICIN
CHEMBL53463
Approved 1974
Properties Compare Identifier
VINBLASTINE
CHEMBL159
Approved 1965
Properties Compare Identifier
Assay Landscape

Assay Landscape

12
Total Assays
136
Tested Compounds
1
Assay Types
Functional — 12 assays, 136 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 12 136 5.6

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine