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Target Snapshot

CHEMBL613589 Target Snapshot

Plasma · TISSUE · Mus musculus

3,436Compounds
3,155Assays
0Approved Drugs
28.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Plasma as ChEMBL target CHEMBL613589. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Plasma
TISSUE · Mus musculus
As of 2026-09-14
ChEMBL target ID
CHEMBL613589
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Plasma still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

Jump to Disease Context
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Evidence Card
Review-ready rationale with source-aware context

Open the one-page evidence card when you want the rationale, activity base, and attribution together.

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelPlasma
UniProt AccessionN/A

Plasma

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Plasma.

Review namePlasma
OrganismMus musculus
Clinical Profile

Clinical Phase Distribution

1
Phase III
Assay Mix

Activity Type Distribution

IC5027.0
EC501.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL487431 7.58 EC50 26.0 Preclinical
CHEMBL5169363 6.96 IC50 110.0 Preclinical
CHEMBL5188279 6.5 IC50 320.0 Preclinical
CHEMBL5206438 6.33 IC50 470.0 Preclinical
CHEMBL5206713 6.24 IC50 570.0 Preclinical
CHEMBL48361 6.22 IC50 600.0 Clinical
Distribution

pChEMBL Value Distribution

0
5.0
0
5.5
3
6.0
2
6.5
0
7.0
1
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

3,162
Total Assays
6
Tested Compounds
3
Assay Types
ADME — 3,070 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 2,297 0
cell-free format 767 0
assay format 3 0
cell-based format 3 0
Functional — 88 assays, 6 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 63 0
cell-free format 24 6 6.6
cell-based format 1 0
Unassigned — 4 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 4 0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine