Liver microsomes · SUBCELLULAR · Rattus norvegicus
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Liver microsomes
Review this target as Liver microsomes.
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This review treats Liver microsomes as ChEMBL target CHEMBL613694. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Liver microsomes |
| Target Type | SUBCELLULAR |
| Organism | Rattus norvegicus |
Reviewable protein naming and mapping context for this target snapshot.
Review this target as Liver microsomes.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL488297 | 9.52 | IC50 | 0.3 | Preclinical |
| CHEMBL521039 | 9.52 | IC50 | 0.3 | Preclinical |
| CHEMBL455524 | 9.3 | IC50 | 0.5 | Preclinical |
| CHEMBL444210 | 9.22 | IC50 | 0.6 | Preclinical |
| CHEMBL504300 | 8.98 | IC50 | 1.04 | Preclinical |
| CHEMBL487631 | 8.96 | IC50 | 1.1 | Preclinical |
| CHEMBL488300 | 8.89 | IC50 | 1.3 | Preclinical |
| CHEMBL501917 | 8.77 | IC50 | 1.7 | Preclinical |
| CHEMBL471744 | 8.74 | IC50 | 1.8 | Preclinical |
| CHEMBL527431 | 8.74 | IC50 | 1.8 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| microsome format | 1,255 | 12 | 5.6 |
| organism-based format | 18 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| microsome format | 51 | 163 | 5.9 |