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Target Snapshot

CHEMBL613711 Target Snapshot

SUD4 · CELL-LINE · Homo sapiens

285Compounds
165Assays
5Approved Drugs
181.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats SUD4 as ChEMBL target CHEMBL613711. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
SUD4
CELL-LINE · Homo sapiens
As of 2026-09-13
ChEMBL target ID
CHEMBL613711
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether SUD4 still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelSUD4
UniProt AccessionN/A

SUD4

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as SUD4.

Review nameSUD4
OrganismHomo sapiens
Clinical Profile

Clinical Phase Distribution

5
Approved
2
Phase III
1
Phase II
1
Phase I
Assay Mix

Activity Type Distribution

IC50170.0
EC5011.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL1090479 8.3 EC50 5.0 Preclinical
CHEMBL4462577 8.12 IC50 7.6 Preclinical
CHEMBL2103840 8.0 IC50 10.0 Clinical
CHEMBL4540226 7.82 IC50 15.0 Preclinical
CHEMBL5079947 7.7 IC50 20.0 Preclinical
CHEMBL5076703 7.7 IC50 20.0 Preclinical
CHEMBL5179238 7.52 IC50 30.0 Preclinical
CHEMBL5272165 7.42 IC50 38.0 Preclinical
CHEMBL5187279 7.3 IC50 50.0 Preclinical
CHEMBL1738758 7.25 IC50 56.0 Clinical
Distribution

pChEMBL Value Distribution

16
5.0
32
5.5
41
6.0
22
6.5
5
7.0
4
7.5
3
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

DUVELISIB
CHEMBL3039502
Approved 2018
IBRUTINIB
CHEMBL1873475
Approved 2013
Assay Landscape

Assay Landscape

165
Total Assays
136
Tested Compounds
2
Assay Types
Functional — 164 assays, 136 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 156 136 6.0
organism-based format 8 0
ADME — 1 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 1 0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine