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Target Snapshot

CHEMBL613721 Target Snapshot

Reovirus sp. · ORGANISM · Reovirus sp.

Back to Search Search this target Browse approvals Evidence Card
317Compounds
16Assays
0Approved Drugs
143.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Reovirus sp. as ChEMBL target CHEMBL613721. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Reovirus sp.
ORGANISM · Reovirus sp.
As of 2026-09-14
ChEMBL target ID
CHEMBL613721
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Reovirus sp. still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

Jump to Disease Context
Need a meeting-ready explanation of why this target matters?
Evidence Card
Review-ready rationale with source-aware context

Open the one-page evidence card when you want the rationale, activity base, and attribution together.

Open Review-ready Card
Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameReovirus sp.
Target TypeORGANISM
OrganismReovirus sp.
ChEMBL ↗ NCBI Taxonomy ↗

Next Actions

SearchRun a focused querySearch the database using this target name as the starting context. ApprovalsCheck approved moleculesSee which approved drugs connect back to this target and its surrounding signal space. FeedScan papers & updatesStay in the project thread while checking recent papers and platform updates.
UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelReovirus sp.
UniProt AccessionN/A

Reovirus sp.

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as Reovirus sp..

Review nameReovirus sp.
OrganismReovirus sp.
Assay Mix

Activity Type Distribution

EC50143.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL418899 5.62 EC50 2400.0 Preclinical
CHEMBL1940449 5.0 EC50 10000.0 Preclinical
CHEMBL1940448 4.89 EC50 13000.0 Preclinical
CHEMBL438605 4.8 EC50 16000.0 Preclinical
CHEMBL3325678 4.57 EC50 27000.0 Preclinical
CHEMBL3325677 4.5 EC50 32000.0 Preclinical
CHEMBL1940468 4.44 EC50 36000.0 Preclinical
CHEMBL1940469 4.33 EC50 47000.0 Preclinical
CHEMBL1940458 4.3 EC50 50000.0 Preclinical
CHEMBL1940454 4.29 EC50 51000.0 Preclinical
Distribution

pChEMBL Value Distribution

1
5.0
1
5.5
0
6.0
0
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

16
Total Assays
12
Tested Compounds
1
Assay Types
Functional — 16 assays, 12 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 16 12 4.6

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine