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Target Snapshot

CHEMBL613725 Target Snapshot

Sindbis virus · ORGANISM · Sindbis virus

Back to Search Search this target Browse approvals Evidence Card
1,470Compounds
160Assays
6Approved Drugs
482.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Sindbis virus as ChEMBL target CHEMBL613725. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Sindbis virus
ORGANISM · Sindbis virus
As of 2026-09-14
ChEMBL target ID
CHEMBL613725
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Sindbis virus still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameSindbis virus
Target TypeORGANISM
OrganismSindbis virus
ChEMBL ↗ NCBI Taxonomy ↗

Next Actions

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelSindbis virus
UniProt AccessionN/A

Sindbis virus

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as Sindbis virus.

Review nameSindbis virus
OrganismSindbis virus
Clinical Profile

Clinical Phase Distribution

6
Approved
1
Phase II
1
Phase I
Assay Mix

Activity Type Distribution

IC5021.0
EC50461.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL486477 8.82 EC50 1.5 Preclinical
CHEMBL3797928 8.7 EC50 2.0 Preclinical
CHEMBL3797928 8.7 IC50 2.0 Preclinical
CHEMBL3798024 8.7 EC50 2.0 Preclinical
CHEMBL3798024 8.7 IC50 2.0 Preclinical
CHEMBL269277 6.34 IC50 457.09 Preclinical
CHEMBL5630521 6.02 EC50 950.0 Preclinical
CHEMBL364472 6.0 EC50 1000.0 Preclinical
CHEMBL3741103 5.94 EC50 1140.0 Preclinical
CHEMBL1336 5.89 EC50 1300.0 Approved
Distribution

pChEMBL Value Distribution

12
5.0
11
5.5
4
6.0
0
6.5
0
7.0
0
7.5
0
8.0
6
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

160
Total Assays
60
Tested Compounds
1
Assay Types
Functional — 160 assays, 60 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 156 57 5.4
assay format 3 2 5.5
cell-based format 1 1 5.8

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine