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Target Snapshot

CHEMBL613728 Target Snapshot

dengue virus type 4 · ORGANISM · dengue virus type 4

Back to Search Search this target Browse approvals Evidence Card
254Compounds
72Assays
4Approved Drugs
272.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats dengue virus type 4 as ChEMBL target CHEMBL613728. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
dengue virus type 4
ORGANISM · dengue virus type 4
As of 2026-09-14
ChEMBL target ID
CHEMBL613728
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether dengue virus type 4 still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

Jump to Disease Context
Need a meeting-ready explanation of why this target matters?
Evidence Card
Review-ready rationale with source-aware context

Open the one-page evidence card when you want the rationale, activity base, and attribution together.

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred Namedengue virus type 4
Target TypeORGANISM
Organismdengue virus type 4
ChEMBL ↗ NCBI Taxonomy ↗

Next Actions

SearchRun a focused querySearch the database using this target name as the starting context. ApprovalsCheck approved moleculesSee which approved drugs connect back to this target and its surrounding signal space. FeedScan papers & updatesStay in the project thread while checking recent papers and platform updates.
UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein Labeldengue virus type 4
UniProt AccessionN/A

dengue virus type 4

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as dengue virus type 4.

Review namedengue virus type 4
Organismdengue virus type 4
Clinical Profile

Clinical Phase Distribution

4
Approved
3
Phase II
1
Phase I
Assay Mix

Activity Type Distribution

IC5037.0
EC50235.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL3905772 7.96 EC50 11.0 Preclinical
CHEMBL5314530 7.96 EC50 11.0 Clinical
CHEMBL5562312 7.96 EC50 11.0 Preclinical
CHEMBL5555759 7.82 EC50 15.0 Preclinical
CHEMBL1630221 7.52 EC50 30.0 Preclinical
CHEMBL4094417 7.52 EC50 30.0 Preclinical
CHEMBL3763180 7.4 EC50 40.0 Preclinical
CHEMBL3923294 7.36 EC50 44.0 Preclinical
CHEMBL4081688 7.3 EC50 50.0 Preclinical
CHEMBL5559307 7.28 EC50 53.0 Preclinical
Distribution

pChEMBL Value Distribution

36
5.0
38
5.5
35
6.0
14
6.5
12
7.0
6
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

SUNITINIB
CHEMBL535
Approved 2006
Properties Compare Identifier
BROMOCRIPTINE
CHEMBL493
Approved 1978
Properties Compare Identifier
Assay Landscape

Assay Landscape

74
Total Assays
147
Tested Compounds
1
Assay Types
Functional — 74 assays, 147 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 72 114 5.8
cell-based format 2 33 6.0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine