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Target Snapshot

CHEMBL613748 Target Snapshot

Rauscher murine leukemia virus · ORGANISM · Rauscher murine leukemia virus

25Compounds
10Assays
1Approved Drugs
10.0Activities
Free Research Context

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Broader Open DB context

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Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

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Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Rauscher murine leukemia virus as ChEMBL target CHEMBL613748. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Rauscher murine leukemia virus
ORGANISM · Rauscher murine leukemia virus
As of 2026-09-14
ChEMBL target ID
CHEMBL613748
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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UniProt Target Context
UniProt accession via ChEMBL component mapping

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelRauscher murine leukemia virus
UniProt AccessionN/A

Rauscher murine leukemia virus

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Rauscher murine leukemia virus.

Review nameRauscher murine leukemia virus
OrganismRauscher murine leukemia virus
Clinical Profile

Clinical Phase Distribution

1
Approved
Assay Mix

Activity Type Distribution

IC5010.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL129 7.64 IC50 23.0 Approved
CHEMBL1791030 6.68 IC50 210.0 Preclinical
CHEMBL1791024 6.64 IC50 230.0 Preclinical
CHEMBL1794993 6.57 IC50 270.0 Preclinical
CHEMBL1794991 4.79 IC50 16100.0 Preclinical
CHEMBL1794994 4.75 IC50 17700.0 Preclinical
Distribution

pChEMBL Value Distribution

0
5.0
0
5.5
0
6.0
3
6.5
0
7.0
1
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

ZIDOVUDINE
CHEMBL129
Approved 1987
Assay Landscape

Assay Landscape

10
Total Assays
8
Tested Compounds
1
Assay Types
Functional — 10 assays, 8 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 10 8 6.2

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine