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Target Snapshot

CHEMBL613752 Target Snapshot

Poliovirus 2 · ORGANISM · Poliovirus 2

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96Compounds
44Assays
0Approved Drugs
79.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Poliovirus 2 as ChEMBL target CHEMBL613752. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Poliovirus 2
ORGANISM · Poliovirus 2
As of 2026-09-13
ChEMBL target ID
CHEMBL613752
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Poliovirus 2 still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NamePoliovirus 2
Target TypeORGANISM
OrganismPoliovirus 2
ChEMBL ↗ NCBI Taxonomy ↗

Next Actions

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelPoliovirus 2
UniProt AccessionN/A

Poliovirus 2

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as Poliovirus 2.

Review namePoliovirus 2
OrganismPoliovirus 2
Clinical Profile

Clinical Phase Distribution

5
Phase II
Assay Mix

Activity Type Distribution

IC508.0
EC5071.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL266800 8.52 IC50 3.0 Preclinical
CHEMBL283639 8.4 IC50 4.0 Clinical
CHEMBL298019 8.3 EC50 5.0 Clinical
CHEMBL25488 8.1 IC50 8.0 Preclinical
CHEMBL2407818 7.89 EC50 13.0 Preclinical
CHEMBL1235858 7.8 EC50 16.0 Preclinical
CHEMBL166427 7.7 EC50 20.0 Preclinical
CHEMBL4542831 7.7 EC50 20.0 Preclinical
CHEMBL4521854 7.58 EC50 26.0 Preclinical
CHEMBL57071 7.4 IC50 40.0 Preclinical
Distribution

pChEMBL Value Distribution

9
5.0
9
5.5
12
6.0
8
6.5
10
7.0
20
7.5
3
8.0
1
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

44
Total Assays
23
Tested Compounds
1
Assay Types
Functional — 44 assays, 23 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 44 23 6.7

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine