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Target Snapshot

CHEMBL613847 Target Snapshot

Cynomolgus monkey · ORGANISM · Macaca fascicularis

1,053Compounds
3,521Assays
1Approved Drugs
11.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Cynomolgus monkey as ChEMBL target CHEMBL613847. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Cynomolgus monkey
ORGANISM · Macaca fascicularis
As of 2026-09-13
ChEMBL target ID
CHEMBL613847
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Cynomolgus monkey still has a stable protein naming contract across sources.

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Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelCynomolgus monkey
UniProt AccessionN/A

Cynomolgus monkey

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Cynomolgus monkey.

Review nameCynomolgus monkey
OrganismMacaca fascicularis
Clinical Profile

Clinical Phase Distribution

1
Approved
2
Phase I
Assay Mix

Activity Type Distribution

IC504.0
EC507.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL3122212 9.37 IC50 0.43 Preclinical
CHEMBL134519 8.56 EC50 2.72 Preclinical
CHEMBL3747562 8.07 EC50 8.5 Preclinical
CHEMBL3683753 7.42 EC50 38.0 Preclinical
CHEMBL4080667 7.12 EC50 75.0 Preclinical
CHEMBL3643413 7.08 IC50 84.0 Approved
CHEMBL3741992 6.52 IC50 300.0 Preclinical
CHEMBL3360975 6.21 EC50 610.0 Preclinical
CHEMBL526305 6.19 IC50 640.0 Preclinical
CHEMBL1956073 5.85 EC50 1410.0 Preclinical
Distribution

pChEMBL Value Distribution

1
5.0
1
5.5
2
6.0
1
6.5
3
7.0
0
7.5
1
8.0
1
8.5
1
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

LENIOLISIB
CHEMBL3643413
Approved 2023
Assay Landscape

Assay Landscape

3,521
Total Assays
11
Tested Compounds
4
Assay Types
ADME — 2,865 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 2,845 0
assay format 20 0
Functional — 512 assays, 11 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 508 11 7.1
assay format 4 0
Toxicity — 141 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 132 0
assay format 9 0
Unassigned — 3 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 3 0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine