Use malaria as the disease frame, then confirm a stable protein accession before cross-source reuse.
CHEMBL613897 Target Snapshot
Ferriprotoporphyrin IX · SMALL MOLECULE · Plasmodium falciparum
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As of 2026-09-14Ferriprotoporphyrin IX shows approved-linked disease relevance led by malaria. 5 more disease programs remain visible in the same review block. 7 linked drugs keep the current disease frame grounded. Use malaria as the disease frame, then confirm a stable protein accession before cross-source reuse.
Ferriprotoporphyrin IX shows approved-linked disease relevance led by malaria. 5 more disease programs remain visible in the same review block. 7 linked drugs remain visible in the same block.
Start review with malaria because it currently carries approved-linked support. Linked drugs include ARTEMETHER, ARTENIMOL, CHLOROQUINE PHOSPHATE, HYDROXYCHLOROQUINE SULFATE. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.
Disease source · ChEMBL drug mechanism + indication proxyFerriprotoporphyrin IX
Review this target as Ferriprotoporphyrin IX.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Ferriprotoporphyrin IX as ChEMBL target CHEMBL613897. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
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Start here when your first question is whether Ferriprotoporphyrin IX still has a stable protein naming contract across sources.
Jump to Protein ContextUse this block first when you need to confirm why malaria is currently framed as approved-linked support. It currently carries 7 linked drugs in the same disease frame.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardBasic Information
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| Preferred Name | Ferriprotoporphyrin IX |
| Target Type | SMALL MOLECULE |
| Organism | Plasmodium falciparum |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
How to read this target
Review this target as Ferriprotoporphyrin IX.
Disease Relevance & Evidence Level
Open Targets-ready disease context using the current target-indication evidence contract.
Ferriprotoporphyrin IX shows approved-linked disease relevance led by malaria. 5 more disease programs remain visible in the same review block.
How to read disease relevance
Start review with malaria because it currently carries approved-linked support. Linked drugs include ARTEMETHER, ARTENIMOL, CHLOROQUINE PHOSPHATE, HYDROXYCHLOROQUINE SULFATE. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL76 | 4.75 | IC50 | 17900.0 | Approved |
pChEMBL Value Distribution
Assay Landscape
Binding — 15 assays, 0 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 15 | 0 | — |
Functional — 9 assays, 16 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 9 | 16 | 4.7 |