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Target Snapshot

CHEMBL613898 Target Snapshot

Hemozoin · MACROMOLECULE · Plasmodium falciparum

241Compounds
56Assays
4Approved Drugs
222.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Hemozoin as ChEMBL target CHEMBL613898. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Hemozoin
MACROMOLECULE · Plasmodium falciparum
As of 2026-09-13
ChEMBL target ID
CHEMBL613898
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Hemozoin still has a stable protein naming contract across sources.

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Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelHemozoin
UniProt AccessionN/A

Hemozoin

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Hemozoin.

Review nameHemozoin
OrganismPlasmodium falciparum
Clinical Profile

Clinical Phase Distribution

4
Approved
1
Phase III
Assay Mix

Activity Type Distribution

IC50222.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL5269049 7.1 IC50 79.0 Preclinical
CHEMBL5279554 6.85 IC50 140.0 Preclinical
CHEMBL76 6.75 IC50 180.0 Approved
CHEMBL5438011 6.72 IC50 190.0 Preclinical
CHEMBL5290580 6.68 IC50 210.0 Preclinical
CHEMBL5283588 6.54 IC50 290.0 Preclinical
CHEMBL5436922 6.54 IC50 290.0 Preclinical
CHEMBL5394575 6.41 IC50 390.0 Preclinical
CHEMBL5274289 6.34 IC50 460.0 Preclinical
CHEMBL5414513 6.32 IC50 480.0 Preclinical
Distribution

pChEMBL Value Distribution

29
5.0
10
5.5
11
6.0
6
6.5
1
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

CHLOROQUINE
CHEMBL76
Approved 1949
Assay Landscape

Assay Landscape

56
Total Assays
120
Tested Compounds
3
Assay Types
Binding — 51 assays, 120 compounds
BAO Format Assays Compounds Avg pChEMBL
assay format 42 120 5.1
cell-based format 9 0
Functional — 4 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
assay format 4 0
Unassigned — 1 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
assay format 1 0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine