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Target Snapshot

CHEMBL614026 Target Snapshot

Breast carcinoma cell · CELL-LINE · Homo sapiens

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115Compounds
65Assays
1Approved Drugs
47.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Breast carcinoma cell as ChEMBL target CHEMBL614026. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Breast carcinoma cell
CELL-LINE · Homo sapiens
As of 2026-09-14
ChEMBL target ID
CHEMBL614026
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Breast carcinoma cell still has a stable protein naming contract across sources.

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Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameBreast carcinoma cell
Target TypeCELL-LINE
OrganismHomo sapiens
ChEMBL ↗

Next Actions

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelBreast carcinoma cell
UniProt AccessionN/A

Breast carcinoma cell

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as Breast carcinoma cell.

Review nameBreast carcinoma cell
OrganismHomo sapiens
Clinical Profile

Clinical Phase Distribution

1
Approved
Assay Mix

Activity Type Distribution

IC5047.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL364622 9.0 IC50 1.0 Preclinical
CHEMBL414281 8.8 IC50 1.6 Preclinical
CHEMBL433958 8.66 IC50 2.2 Preclinical
CHEMBL4216044 8.3 IC50 5.0 Preclinical
CHEMBL449686 7.36 IC50 44.0 Preclinical
CHEMBL5286285 7.26 IC50 55.0 Preclinical
CHEMBL4439079 6.42 IC50 380.0 Preclinical
CHEMBL4303369 6.41 IC50 390.0 Preclinical
CHEMBL555017 6.38 IC50 420.0 Preclinical
CHEMBL1762708 6.29 IC50 510.0 Preclinical
Distribution

pChEMBL Value Distribution

3
5.0
1
5.5
9
6.0
0
6.5
2
7.0
0
7.5
1
8.0
2
8.5
1
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

65
Total Assays
32
Tested Compounds
1
Assay Types
Functional — 65 assays, 32 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 43 31 5.6
organism-based format 18 0 —
assay format 4 1 8.3

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine