CCRF S-180 · CELL-LINE · Mus musculus
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CCRF S-180
Review this target as CCRF S-180.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats CCRF S-180 as ChEMBL target CHEMBL614027. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | CCRF S-180 |
| Target Type | CELL-LINE |
| Organism | Mus musculus |
Reviewable protein naming and mapping context for this target snapshot.
Review this target as CCRF S-180.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL155956 | 8.77 | IC50 | 1.7 | Preclinical |
| CHEMBL136010 | 8.72 | IC50 | 1.9 | Preclinical |
| CHEMBL422395 | 8.71 | IC50 | 1.97 | Preclinical |
| CHEMBL114987 | 8.63 | IC50 | 2.35 | Preclinical |
| CHEMBL337051 | 8.59 | IC50 | 2.6 | Preclinical |
| CHEMBL341401 | 8.42 | IC50 | 3.8 | Preclinical |
| CHEMBL132142 | 8.41 | IC50 | 3.9 | Preclinical |
| CHEMBL134817 | 8.41 | IC50 | 3.9 | Preclinical |
| CHEMBL34259 | 8.27 | IC50 | 5.4 | Approved |
| CHEMBL335716 | 8.23 | IC50 | 5.9 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| organism-based format | 265 | 0 | — |
| cell-based format | 76 | 71 | 5.7 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 4 | 3 | 4.4 |
| organism-based format | 4 | 0 | — |