A-431 · CELL-LINE · Homo sapiens
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A-431
Review this target as A-431.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats A-431 as ChEMBL target CHEMBL614069. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | A-431 |
| Target Type | CELL-LINE |
| Organism | Homo sapiens |
Reviewable protein naming and mapping context for this target snapshot.
Review this target as A-431.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2324630 | 10.74 | IC50 | 0.018 | Preclinical |
| CHEMBL1173655 | 10.64 | IC50 | 0.023 | Approved |
| CHEMBL292702 | 10.4 | IC50 | 0.04 | Clinical |
| CHEMBL2324629 | 10.19 | IC50 | 0.064 | Preclinical |
| CHEMBL94657 | 10.14 | IC50 | 0.073 | Clinical |
| CHEMBL126678 | 10.05 | IC50 | 0.09 | Preclinical |
| CHEMBL888 | 9.74 | IC50 | 0.1831 | Approved |
| CHEMBL2324627 | 9.72 | IC50 | 0.19 | Preclinical |
| CHEMBL153231 | 9.3 | IC50 | 0.5 | Preclinical |
| CHEMBL215032 | 9.26 | IC50 | 0.55 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 818 | 2,598 | 5.7 |
| organism-based format | 174 | 2 | 6.5 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 45 | 175 | 5.5 |
| organism-based format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 25 | 49 | 5.5 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 0 | — |