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Target Snapshot

CHEMBL614074 Target Snapshot

V79 · CELL-LINE · Cricetulus griseus

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822Compounds
210Assays
7Approved Drugs
737.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats V79 as ChEMBL target CHEMBL614074. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
V79
CELL-LINE · Cricetulus griseus
As of 2026-09-13
ChEMBL target ID
CHEMBL614074
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether V79 still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameV79
Target TypeCELL-LINE
OrganismCricetulus griseus
ChEMBL ↗

Next Actions

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelV79
UniProt AccessionN/A

V79

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as V79.

Review nameV79
OrganismCricetulus griseus
Clinical Profile

Clinical Phase Distribution

7
Approved
3
Phase III
3
Phase II
Assay Mix

Activity Type Distribution

IC50737.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL288377 10.1 IC50 0.08 Preclinical
CHEMBL2158075 10.0 IC50 0.1 Preclinical
CHEMBL37705 9.48 IC50 0.33 Preclinical
CHEMBL144896 9.4 IC50 0.4 Preclinical
CHEMBL1256991 9.4 IC50 0.4 Preclinical
CHEMBL1256965 9.3 IC50 0.5 Preclinical
CHEMBL1257018 9.1 IC50 0.8 Preclinical
CHEMBL1257017 8.7 IC50 2.0 Preclinical
CHEMBL2158071 8.7 IC50 2.0 Preclinical
CHEMBL2158072 8.7 IC50 2.0 Preclinical
Distribution

pChEMBL Value Distribution

61
5.0
39
5.5
26
6.0
30
6.5
18
7.0
7
7.5
4
8.0
9
8.5
6
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

MITOMYCIN
CHEMBL105
Approved 1981
Properties Compare Identifier
DOXORUBICIN
CHEMBL53463
Approved 1974
Properties Compare Identifier
Assay Landscape

Assay Landscape

216
Total Assays
231
Tested Compounds
4
Assay Types
Functional — 156 assays, 231 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 156 231 5.5
ADME — 49 assays, 128 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 49 128 5.4
Toxicity — 7 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 7 0 —
Unassigned — 4 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 4 0 —

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine