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Target Snapshot

CHEMBL614078 Target Snapshot

MDA-N · CELL-LINE · Homo sapiens

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27,401Compounds
88Assays
0Approved Drugs
17.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats MDA-N as ChEMBL target CHEMBL614078. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
MDA-N
CELL-LINE · Homo sapiens
As of 2026-09-14
ChEMBL target ID
CHEMBL614078
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether MDA-N still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

Jump to Disease Context
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Evidence Card
Review-ready rationale with source-aware context

Open the one-page evidence card when you want the rationale, activity base, and attribution together.

Open Review-ready Card
Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameMDA-N
Target TypeCELL-LINE
OrganismHomo sapiens
ChEMBL ↗

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelMDA-N
UniProt AccessionN/A

MDA-N

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as MDA-N.

Review nameMDA-N
OrganismHomo sapiens
Assay Mix

Activity Type Distribution

IC5017.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL38957 8.65 IC50 2.22 Preclinical
CHEMBL334648 8.52 IC50 3.0 Preclinical
CHEMBL341800 8.1 IC50 8.0 Preclinical
CHEMBL136396 7.85 IC50 14.0 Preclinical
CHEMBL136268 7.68 IC50 21.0 Preclinical
CHEMBL267616 7.29 IC50 51.0 Preclinical
CHEMBL7063 7.21 IC50 61.0 Preclinical
CHEMBL136985 7.09 IC50 82.0 Preclinical
CHEMBL435984 7.08 IC50 83.0 Preclinical
CHEMBL258765 6.25 IC50 560.0 Preclinical
Distribution

pChEMBL Value Distribution

2
5.0
0
5.5
2
6.0
0
6.5
4
7.0
2
7.5
1
8.0
2
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

88
Total Assays
13
Tested Compounds
1
Assay Types
Functional — 88 assays, 13 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 87 13 7.1
organism-based format 1 0 —

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine