RT-112 · CELL-LINE · Homo sapiens
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RT-112
Review this target as RT-112.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats RT-112 as ChEMBL target CHEMBL614145. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | RT-112 |
| Target Type | CELL-LINE |
| Organism | Homo sapiens |
Reviewable protein naming and mapping context for this target snapshot.
Review this target as RT-112.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL888 | 9.89 | IC50 | 0.1273 | Approved |
| CHEMBL3348846 | 9.22 | IC50 | 0.6 | Clinical |
| CHEMBL94657 | 9.21 | IC50 | 0.6143 | Clinical |
| CHEMBL3545252 | 8.93 | IC50 | 1.187 | Approved |
| CHEMBL3545376 | 8.89 | IC50 | 1.3 | Approved |
| CHEMBL159 | 8.57 | IC50 | 2.708 | Approved |
| CHEMBL4297522 | 8.48 | IC50 | 3.3 | Approved |
| CHEMBL553025 | 8.47 | IC50 | 3.371 | Approved |
| CHEMBL5314537 | 8.4 | IC50 | 4.0 | Clinical |
| CHEMBL96926 | 8.38 | IC50 | 4.217 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 80 | 210 | 6.0 |
| organism-based format | 9 | 0 | — |