Skip to main content
Free research Free research Free target review with research home and workspace preview
Quick search ChEMBL 36
Loading Target Snapshot...
Querying ChEMBL database. This may take a few seconds.
Target Snapshot

CHEMBL614151 Target Snapshot

CRL-7065 cell line · CELL-LINE · Homo sapiens

20Compounds
3Assays
2Approved Drugs
21.0Activities
Free Research Context

Research home keeps recent targets

This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.

Navigation

Switch target

Move to another high-traffic target or paste a specific ChEMBL target ID.

Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats CRL-7065 cell line as ChEMBL target CHEMBL614151. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
CRL-7065 cell line
CELL-LINE · Homo sapiens
As of 2026-09-13
ChEMBL target ID
CHEMBL614151
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether CRL-7065 cell line still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

Jump to Disease Context
Need a meeting-ready explanation of why this target matters?
Evidence Card
Review-ready rationale with source-aware context

Open the one-page evidence card when you want the rationale, activity base, and attribution together.

Open Review-ready Card
Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelCRL-7065 cell line
UniProt AccessionN/A

CRL-7065 cell line

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as CRL-7065 cell line.

Review nameCRL-7065 cell line
OrganismHomo sapiens
Clinical Profile

Clinical Phase Distribution

2
Approved
Assay Mix

Activity Type Distribution

IC5021.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL1554 8.15 IC50 7.0 Approved
CHEMBL355741 7.4 IC50 40.0 Preclinical
CHEMBL436051 7.3 IC50 50.0 Preclinical
CHEMBL168653 7.16 IC50 70.0 Preclinical
CHEMBL169393 7.05 IC50 90.0 Preclinical
CHEMBL53463 6.3 IC50 500.0 Approved
CHEMBL151423 6.3 IC50 500.0 Preclinical
CHEMBL348434 6.09 IC50 810.0 Preclinical
CHEMBL168964 6.05 IC50 900.0 Preclinical
CHEMBL170164 5.89 IC50 1300.0 Preclinical
Distribution

pChEMBL Value Distribution

0
5.0
3
5.5
5
6.0
0
6.5
4
7.0
0
7.5
1
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

DOXORUBICIN
CHEMBL53463
Approved 1974
DACTINOMYCIN
CHEMBL1554
Approved 1964
Assay Landscape

Assay Landscape

3
Total Assays
12
Tested Compounds
1
Assay Types
Functional — 3 assays, 12 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 3 12 6.6

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine