Confirm a stable target identifier before relying on this context across project surfaces.
CHEMBL614300 Target Snapshot
SR · CELL-LINE · Homo sapiens
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As of 2026-09-14Confirm a stable target identifier before relying on this context across project surfaces.
SR
Review this target as SR.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats SR as ChEMBL target CHEMBL614300. Disease framing currently uses the Open Targets-ready proxy contract.
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Open Review-ready CardBasic Information
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| Preferred Name | SR |
| Target Type | CELL-LINE |
| Organism | Homo sapiens |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
How to read this target
Review this target as SR.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL220241 | 9.86 | IC50 | 0.1371 | Preclinical |
| CHEMBL18155 | 9.38 | IC50 | 0.42 | Preclinical |
| CHEMBL150607 | 9.35 | IC50 | 0.45 | Preclinical |
| CHEMBL4849206 | 9.3 | IC50 | 0.5 | Preclinical |
| CHEMBL38957 | 9.25 | IC50 | 0.562 | Preclinical |
| CHEMBL3747525 | 9.1 | IC50 | 0.8 | Preclinical |
| CHEMBL4851806 | 9.05 | IC50 | 0.9 | Preclinical |
| CHEMBL4851115 | 8.96 | IC50 | 1.1 | Preclinical |
| CHEMBL4849830 | 8.92 | IC50 | 1.2 | Preclinical |
| CHEMBL325041 | 8.9 | IC50 | 1.255 | Clinical |
pChEMBL Value Distribution
Approved Drugs
Assay Landscape
Functional — 996 assays, 187 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 996 | 187 | 6.8 |
ADME — 11 assays, 13 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 11 | 13 | 5.7 |