MDA-MB-453 · CELL-LINE · Homo sapiens
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MDA-MB-453
Review this target as MDA-MB-453.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats MDA-MB-453 as ChEMBL target CHEMBL614334. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | MDA-MB-453 |
| Target Type | CELL-LINE |
| Organism | Homo sapiens |
Reviewable protein naming and mapping context for this target snapshot.
Review this target as MDA-MB-453.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4855608 | 9.3 | IC50 | 0.5 | Preclinical |
| CHEMBL4473875 | 9.21 | IC50 | 0.62 | Preclinical |
| CHEMBL4557964 | 9.17 | IC50 | 0.68 | Preclinical |
| CHEMBL428647 | 9.15 | IC50 | 0.7 | Approved |
| CHEMBL4871913 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL4468642 | 8.96 | IC50 | 1.1 | Preclinical |
| CHEMBL4520878 | 8.92 | IC50 | 1.2 | Preclinical |
| CHEMBL5081479 | 8.85 | IC50 | 1.4 | Preclinical |
| CHEMBL4876166 | 8.85 | IC50 | 1.4 | Preclinical |
| CHEMBL4456300 | 8.78 | IC50 | 1.65 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 261 | 574 | 6.0 |
| organism-based format | 25 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 3 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 2 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 0 | — |