MEF · CELL-LINE · Mus musculus
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MEF
Review this target as MEF.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats MEF as ChEMBL target CHEMBL614342. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | MEF |
| Target Type | CELL-LINE |
| Organism | Mus musculus |
Reviewable protein naming and mapping context for this target snapshot.
Review this target as MEF.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1738841 | 9.52 | IC50 | 0.3 | Preclinical |
| CHEMBL1762148 | 8.8 | IC50 | 1.6 | Preclinical |
| CHEMBL376408 | 8.69 | EC50 | 2.03 | Preclinical |
| CHEMBL2441342 | 8.4 | IC50 | 4.0 | Preclinical |
| CHEMBL2171124 | 8.14 | IC50 | 7.3 | Preclinical |
| CHEMBL1762178 | 8.1 | IC50 | 8.0 | Preclinical |
| CHEMBL5189423 | 8.0 | IC50 | 10.0 | Preclinical |
| CHEMBL1689145 | 7.94 | EC50 | 11.6 | Preclinical |
| CHEMBL3287301 | 7.85 | IC50 | 14.0 | Preclinical |
| CHEMBL1689143 | 7.8 | EC50 | 16.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 245 | 79 | 5.9 |
| organism-based format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 65 | 115 | 5.1 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 50 | 6 | 7.3 |