BT-474 · CELL-LINE · Homo sapiens
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BT-474
Review this target as BT-474.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats BT-474 as ChEMBL target CHEMBL614529. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | BT-474 |
| Target Type | CELL-LINE |
| Organism | Homo sapiens |
Reviewable protein naming and mapping context for this target snapshot.
Review this target as BT-474.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2204502 | 10.0 | IC50 | 0.1 | Preclinical |
| CHEMBL3326884 | 9.72 | IC50 | 0.19 | Preclinical |
| CHEMBL553025 | 9.52 | IC50 | 0.3 | Approved |
| CHEMBL5590309 | 9.1 | IC50 | 0.8 | Preclinical |
| CHEMBL3326882 | 9.06 | IC50 | 0.88 | Preclinical |
| CHEMBL5570209 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL1099297 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL5181694 | 8.76 | IC50 | 1.75 | Preclinical |
| CHEMBL3128043 | 8.74 | IC50 | 1.8 | Preclinical |
| CHEMBL3325463 | 8.73 | IC50 | 1.85 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 521 | 888 | 6.1 |
| organism-based format | 75 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 8 | 39 | 5.3 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 6 | 0 | — |