COS-1 · CELL-LINE · Chlorocebus aethiops
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COS-1
Review this target as COS-1.
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This review treats COS-1 as ChEMBL target CHEMBL614563. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | COS-1 |
| Target Type | CELL-LINE |
| Organism | Chlorocebus aethiops |
Reviewable protein naming and mapping context for this target snapshot.
Review this target as COS-1.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL423680 | 7.3 | IC50 | 50.0 | Preclinical |
| CHEMBL92499 | 7.16 | IC50 | 70.0 | Preclinical |
| CHEMBL298734 | 7.12 | IC50 | 75.0 | Approved |
| CHEMBL88432 | 7.12 | IC50 | 75.0 | Preclinical |
| CHEMBL89304 | 7.07 | IC50 | 85.0 | Preclinical |
| CHEMBL88713 | 7.0 | IC50 | 100.0 | Preclinical |
| CHEMBL328713 | 7.0 | IC50 | 100.0 | Preclinical |
| CHEMBL313635 | 7.0 | IC50 | 100.0 | Preclinical |
| CHEMBL443022 | 6.96 | IC50 | 110.0 | Preclinical |
| CHEMBL90050 | 6.92 | IC50 | 120.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 22 | 16 | 4.7 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 13 | 42 | 6.1 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 0 | — |