HT-1080 · CELL-LINE · Homo sapiens
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HT-1080
Review this target as HT-1080.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats HT-1080 as ChEMBL target CHEMBL614580. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | HT-1080 |
| Target Type | CELL-LINE |
| Organism | Homo sapiens |
Reviewable protein naming and mapping context for this target snapshot.
Review this target as HT-1080.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5082180 | 10.1 | IC50 | 0.08 | Preclinical |
| CHEMBL553025 | 10.0 | IC50 | 0.1 | Approved |
| CHEMBL159 | 10.0 | IC50 | 0.099 | Approved |
| CHEMBL96926 | 9.95 | IC50 | 0.112 | Preclinical |
| CHEMBL56157 | 9.85 | IC50 | 0.14 | Preclinical |
| CHEMBL428647 | 9.82 | IC50 | 0.15 | Approved |
| CHEMBL5270787 | 9.52 | IC50 | 0.3 | Preclinical |
| CHEMBL90555 | 9.52 | IC50 | 0.3 | Approved |
| CHEMBL123626 | 9.51 | IC50 | 0.31 | Preclinical |
| CHEMBL65 | 9.4 | IC50 | 0.3944 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 925 | 1,666 | 5.9 |
| organism-based format | 43 | 0 | — |
| assay format | 1 | 19 | 6.8 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 22 | 15 | 5.6 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 4 | 0 | — |