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Target Snapshot

CHEMBL614667 Target Snapshot

Ovarian carcinoma cell · CELL-LINE · Homo sapiens

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85Compounds
27Assays
0Approved Drugs
44.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Ovarian carcinoma cell as ChEMBL target CHEMBL614667. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Ovarian carcinoma cell
CELL-LINE · Homo sapiens
As of 2026-09-14
ChEMBL target ID
CHEMBL614667
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Ovarian carcinoma cell still has a stable protein naming contract across sources.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameOvarian carcinoma cell
Target TypeCELL-LINE
OrganismHomo sapiens
ChEMBL ↗

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelOvarian carcinoma cell
UniProt AccessionN/A

Ovarian carcinoma cell

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as Ovarian carcinoma cell.

Review nameOvarian carcinoma cell
OrganismHomo sapiens
Assay Mix

Activity Type Distribution

IC5044.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL41728 5.23 IC50 5888.44 Preclinical
CHEMBL40266 4.4 IC50 39810.72 Preclinical
CHEMBL43690 4.39 IC50 40738.03 Preclinical
CHEMBL285295 4.35 IC50 44668.36 Preclinical
CHEMBL40267 4.25 IC50 56234.13 Preclinical
CHEMBL290894 4.24 IC50 57543.99 Preclinical
CHEMBL282939 4.18 IC50 66069.34 Preclinical
CHEMBL39346 4.15 IC50 70794.58 Preclinical
CHEMBL433630 4.14 IC50 72443.6 Preclinical
CHEMBL290939 4.11 IC50 77624.71 Preclinical
Distribution

pChEMBL Value Distribution

1
5.0
0
5.5
0
6.0
0
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

27
Total Assays
11
Tested Compounds
2
Assay Types
Functional — 26 assays, 11 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 26 11 4.3
ADME — 1 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 1 0 —

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine