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Target Snapshot

CHEMBL614676 Target Snapshot

Liposome · SUBCELLULAR

87Compounds
55Assays
0Approved Drugs
80.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Liposome as ChEMBL target CHEMBL614676. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Liposome
SUBCELLULAR
As of 2026-09-13
ChEMBL target ID
CHEMBL614676
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Liposome still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

Jump to Disease Context
Need a meeting-ready explanation of why this target matters?
Evidence Card
Review-ready rationale with source-aware context

Open the one-page evidence card when you want the rationale, activity base, and attribution together.

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelLiposome
UniProt AccessionN/A

Liposome

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Liposome.

Review nameLiposome
Clinical Profile

Clinical Phase Distribution

1
Phase II
Assay Mix

Activity Type Distribution

IC5080.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL437913 6.47 IC50 340.0 Preclinical
CHEMBL52 5.7 IC50 2000.0 Preclinical
CHEMBL274908 5.52 IC50 3000.0 Preclinical
CHEMBL433067 5.52 IC50 3000.0 Preclinical
CHEMBL47046 5.4 IC50 4000.0 Preclinical
CHEMBL417717 5.4 IC50 4000.0 Preclinical
CHEMBL46487 5.3 IC50 5000.0 Preclinical
CHEMBL44921 5.16 IC50 7000.0 Preclinical
CHEMBL12932 5.1 IC50 8000.0 Preclinical
CHEMBL13204 4.96 IC50 11000.0 Preclinical
Distribution

pChEMBL Value Distribution

7
5.0
5
5.5
6
6.0
0
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

55
Total Assays
48
Tested Compounds
2
Assay Types
Functional — 50 assays, 48 compounds
BAO Format Assays Compounds Avg pChEMBL
subcellular format 35 30 5.1
microsome format 15 18 4.6
Binding — 5 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
subcellular format 3 0
microsome format 2 0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine