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Target Snapshot

CHEMBL614773 Target Snapshot

SW-1736 · CELL-LINE · Homo sapiens

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337Compounds
36Assays
0Approved Drugs
285.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats SW-1736 as ChEMBL target CHEMBL614773. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
SW-1736
CELL-LINE · Homo sapiens
As of 2026-09-14
ChEMBL target ID
CHEMBL614773
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether SW-1736 still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

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Evidence Card
Review-ready rationale with source-aware context

Open the one-page evidence card when you want the rationale, activity base, and attribution together.

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameSW-1736
Target TypeCELL-LINE
OrganismHomo sapiens
ChEMBL ↗

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelSW-1736
UniProt AccessionN/A

SW-1736

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as SW-1736.

Review nameSW-1736
OrganismHomo sapiens
Clinical Profile

Clinical Phase Distribution

1
Phase II
2
Phase I
Assay Mix

Activity Type Distribution

IC50138.0
EC50147.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL9941 7.56 IC50 27.5 Preclinical
CHEMBL4176040 7.52 EC50 30.0 Preclinical
CHEMBL4160690 7.4 EC50 40.0 Preclinical
CHEMBL4175027 7.4 EC50 40.0 Preclinical
CHEMBL4160915 7.3 EC50 50.0 Preclinical
CHEMBL4160108 6.82 EC50 150.0 Preclinical
CHEMBL388978 6.7 EC50 200.0 Preclinical
CHEMBL4165430 6.66 EC50 220.0 Preclinical
CHEMBL4164094 6.62 EC50 240.0 Preclinical
CHEMBL4160966 6.57 EC50 270.0 Preclinical
Distribution

pChEMBL Value Distribution

69
5.0
35
5.5
3
6.0
5
6.5
3
7.0
2
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

36
Total Assays
199
Tested Compounds
2
Assay Types
Functional — 35 assays, 199 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 35 199 5.2
ADME — 1 assays, 2 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 1 2 5.0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine